Sheen's genitals are on-screen on several occasions, but are pixelated each time.

A character lets candlewax drip onto his crotch and gasps in pleasure.

A character is shown pinching and twisting his nipples.

Some scenes of masturbation. Nudity is either out of frame or obscured during these scenes.

A good amount of sexual references (ball-gags, rape, etc.). While some episodes are filled with them, others are perfectly harmless.

Fatigue's mother is a stripper (seen onscreen a few times; no nudity).

One scene of oral sex (off screen).

One quick scene of anal sex (thrusting is seen; no nudity).

Rare bloody violence. eg. Fatigue is briefly shown with a bloody nose near the end of Hang Up, and Andrew W.K. has a rather bloody nosebleed after being punched in the face towards the end of Next Door.

Some comic violence; nothing graphic.

The strong expletive "fuck" is used regularly.

Moderate language, such as "bitch" and "damn."

Roofies are mentioned.

Sheen is seen drinking on many occasions, and is described as abusive when he's drunk.

Sheen is briefly shown raping Fatigue. Fatigue shouts "Dislike!" twice. One episode is titled The 12 Rapes of Christmas. Sheen is shown to be very pushy with sexual demands from Fatigue, while Fatigue is often aloof.

As a comedy series, The Bedfellows has zero scenes of horror, intensity, or even violence, but the sheer amount of sexual references could be worrying.

One episode (Rap Song) uses rapping as one big, obvious allegory to rape.