Sexual innuendo

There's a running joke that Tommy is a homosexual.

Juanita Titus is a schizophrenic manic-depressive and she usually threatens people.

Lots of domestic abuse and child abuse is seen throughout the flashbacks of Titus' childhood.

Erin learns that Titus' first girlfriend was abusive, and he was the victim of domestic abuse.

A lot of swearing and name-calling

Ken Titus is an alcoholic, also Titus is revealed to have been a drinker as a teenager.

Dave supposedly has an addiction to marijuana.

Juanita takes medicine for her disorder, and in one episode she spikes food with it so everyone falls asleep.

The episode where Ken has a heart attack might be too intense for some viewers.

The scenes where Juanita relapses from her disorder might be frightening to some viewers

Titus is involved in an accident and is pronounced brain-dead, he however recovers. This may be a little too thematic for some viewers.

Overall this series has dark-comedy and thematic elements.