No obvious sex or nudity.

In one episode, a young prostitute was brought into the hospital having been beaten by her "uncle" who turns out to be her father. She tells the nurse that her father "will go easier on her" if she does what he wants--repeatedly having sex with her.

This series takes place in the major hospital in London in the very early 1900s, where only the "poorest of the poor" are served. That said, victims of many accidents, and diseases that are mostly only seen in history books, are portrayed with the accompanying "blood and gore" of primitive, graphic surgeries.

None

Self-injection of cocaine by physician.

Many of the poor are seen drunk in the streets, and with bottles in their hands. Drunks admitted for accidents as a result of their alcoholism.

A few instances of cigarette smoking, but not out of the normal context.

Throughout the series there are scenes depicting surgeries, including amputations and incisions, with accompanying pain and blood.