It's implied Fred's mother is a prostitute.

Constant references but no actual sex shown

There is violence in only one episode, a character is shot in the face, blood splatters on the wall behind them and the injury is shown in graphic detail.

Fred often says "oh my gammit" which is a clear reference to "damnit."

Other mild profanity like "hell" "crap" and "sucks"

It is implied that Fred's mom is drunk in many videos