The entire plot and character interaction heavily rely on sex

Sex scenes are very brief but very intimate.

Nude characters are constantly seen throughout the series, breasts and private parts are always covered though.

Sex, and sex related topics are brought up throughout the series, such as when the characters are forced to wear sexual inhibitors (cuts sexual interests in others) they make a bet with the women that they can still get erections with them on.

The characters are briefly seen in a strip club

The team goes to bars constantly in flashbacks.

There is no drinking in the ship.

A character uses patches to relive craving for alcohol.