Nudity is so far not a large part of the show, however what skin is shown belongs to plastic dolls (Barbie brand, for the most part). Sex, however, is mentioned quite frequently through various insults, not-so-subtle innuendo and discussion between characters.
Violence & Gore
Mild
Slapstick violence throughout, tho there are some scenes that are bloody.
Profanity
Severe
Profanity abounds throughout the series shamelessly. The main characters use a variety of inappropriate language and this is so characteristic of them that there is even a sub-plot in Season 2 which forces two of the most profane characters to watch their mouths for a period of time (to almost no avail). Much of the dialogue features cursing to multiple degrees.
Alcohol, Drugs & Smoking
Mild
Bridgett admitted to using heroin and huffing paint.
The Van Buren's mother is an alcoholic and a drug consumer.
Jenna accuses the cheerleaders for scoring crack cocaine and attempting to cook meth.