Numerous photos in slideshows throughout the film show nudity. This includes male and female frontal nudity.

There's a brief section where Goldin talks about taking photos of sexual encounters. This includes some images of real sex, which includes erect penises.

Very disturbing story about domestic violence is recounted. No live-action footage, but photos of a woman's face show serious injuries, with the impact of the story and the visuals together being quite strong.

Drug use and addiction are signficant parts of the documentary, with many stories and visuals relating to drugs seen and heard throughout.

Deals with many heavy and/or disturbing themes over the course of two hours. These include mental illness, addiction, corruption, the AIDS crisis, discrimination, and domestic violence. The stories are usually more intense than the visuals, but it still makes for a harrowing and very sad documentary.