There are scenes where the main character, Greg Heffley, is seen wearing his underwear.

Greg shows Rodrick a picture of woman in a bikini of a convention on his phone. Rodrick asks if those are real (likely referring to her well endowed boobs), and Greg, thinking he means her weapons, says he doubts it, saying people make their weapons out of foam and stuff. No nudity is shown.

When the family is driving Greg Heffley urgently has to use the bathroom. Instead of waiting to get to a rest stop or something he pees in a plastic cup in the car.

Curse words are not heard in this film, however there is name calling. Words like loser, jerk, and dork are said. There are two "Oh my God".

A man presses on another man's stomach, making him vomit onto the man's face. This may be disturbing for young viewers.

Rodrick Wears an Avenged Sevenfold Shirt which can be uncomfortable for younger viewers