Curly's wife flirts with all the men with the exception of her own husband, no sex is shown or implied

There is talk of visiting a cat house

There is talk of a man who keeps his hands soft with vaseline for his wife

Derogatory words are used to describe women and blacks

The most graphic scene is when Curly and Lennie are having a fight. Lenny starts getting hit a lot and his face is seen with bloody injury detail. Then he grabs Curly's hand and starts crushing and breaking it. Blood is seen going down his hand. This scene is graphic and quite hard to watch.

A bunkhouse row, a shooting, and a character gets his fist crushed in another character's powerful hand in a scene that's painful to watch.

A person's neck is broken and he/she dies.

A man is shot behind the head, the shot of this scene is rather distant and not very graphic as it is shocking

A man is shown without a hand

Offscreen, while Candy is laying down crying in bed, his dog is shot and killed by Carlson. Very sad to see and hear as the gunshot is also heard.

10+ Uses of 'God'

20+ Uses of "Damn" and "God Damn"

Infrequent use of 'Son Of A Bitch'

Other milder profanities found in most other PG-13 movies

2 uses of "Nigger", but in historical context.

A few scenes show the main characters smoking, and there is also infrequent talk of buying alcohol.

The film is very sad and intense. And one scene with curly and lenny (check the violence and gore section for more detail) is graphic.