Two young men repeatedly discuss the prospect of finding and sleeping with girlfriends on their trip across the continent.

A woman tells a man that a local river dolphin has sex organs like those of a woman, and that indigenous men nearby have sex with them. The discussion isn't very graphic.

A young man solicits the services of a prostitute. They are shown going into a ship's cabin and closing the door. Sex is implied.

A young man and young woman kiss in the backseat of a car. Sex is implied.

Two men crash several times on a motorcycle.

Many f-words in the English subtitles, some of those mistranslated from milder Spanish terms. Several s-words also.

Some drinking and smoking. Some characters are shown drunk.

A group of people, including children, chew coca leaves.

Alcohol and yerba mate consumption in some scenes.

Throughout the film there are frank and very uncompromising depictions of the hardship, struggle, and poverty of peasant and working-class life in Latin America. While non-graphic and not visually violent, these depictions can be haunting.

A man with asthma swims across a wide river. We are told nobody has ever tried it before.

A man suffers with an asthma attack, another man soothes him and tries to make him feel better.