A scene where a person implies sexual-favor blackmail on another person. Later confesses it as a joke. (Very Rude)
A scene where a character says he slept with someone, and another person perceives this to mean he had sex with them. It's revealed shortly after that he meant he literally slept in the same bed as someone.
Violence & Gore
Mild
I would say this is very mild. There is only one scene where there is any direct gore. A man runs into a wall with a window and on the outside you see a red smear. Also, in another scene you see a man hanging who is dead. There is also a man who shoots himself in the head off camera, but all is seen is a blood splatter on the ground. Lastly, a man walks into a burning building, nothing is seen but his death is implied.
Profanity
Severe
43 uses of "f*ck", 17 of "sh*t", 3 "damn"/"Godd*mn", 3 "h*ll", 3 of "d*ck", 1 "c*ck", 2 "b*tch", 1 "ass", 2 religious exclamations, and 1 use each of "retarded" and "mongoloid".
Alcohol, Drugs & Smoking
Mild
There are many references to using drugs. Crack, meth and "red flower" are the three I remember. However, only the "red flower" is seen being smoked. Most of the characters drink beer regularly that they make themselves. Some characters are shown drunk/high.
A character is handcuffed to rehab him from his drug addiction.
Frightening & Intense Scenes
Moderate
Suicide by hanging, gunshot, and fire. Frequent talk about suicide.